Synthesis of Eight 1-Deoxynojirimycin Isomers from a Single Chiral Cyanohydrin
نویسندگان
چکیده
منابع مشابه
Chiral lithium binaphtholate aqua complex as a highly effective asymmetric catalyst for cyanohydrin synthesis.
A highly enantioselective cyanohydrin synthesis with aromatic aldehydes using chiral lithium binaphtholate aqua or alcohol complexes has been developed and is a simple and inexpensive catalyst suitable for process chemistry to give gram-scale cyanohydrins successfully. Dramatic improvements in enantiomeric excess have been realized along with an interesting changeover in absolute stereochemistr...
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2012
ISSN: 1434-193X
DOI: 10.1002/ejoc.201200377